Author: Robert Zimmerman

Two-thirds of all approved cancer drugs do nothing for patients

4:26 pm

A long term study in Sweden of 22 cancer drugs that its government had approved for rapid use before being tested fully has found that two-thirds provided absolute no benefit to patients.

The Gothenburg team examined 22 cancer drugs approved for reimbursement in Sweden over the last 10 years, examining studies that tested their ability to improve quality of life or lengthen lifespans. On average, these reports examined the drugs for 6.6 years.

Results revealed only seven of the 22 drugs had at least one study which showed a clear benefit for cancer patients. Randomized controlled trials on the other 15 failed to show any tangible benefits for people with cancer. Only one drug in the study showed an ability to both improve the quality of life and extend lifespans for patients.

“We have shown that the majority of the drugs launched with limited evidence still lack clear evidence of how they actually affect survival and quality of life in patients,” says Gabriella Chauca Strand, a doctoral student at Sahlgrenska Academy at the University of Gothenburg and the lead author of the study, in a university release.

This sentence from the university’s press release was even more striking:

Only one of the drugs had scientific evidence of both increased life expectancy and improved quality of life for its indication.

Essentially, 95% of these approved drugs were failures. Most did nothing and were worthless, despite the Swedish government paying huge amounts of money buying them. A few either improved the quality of life (but failed to keep the patient alive) or kept the patient alive longer (but made their lives miserable).

Does this sound familiar? Doesn’t make you wonder about the drug approval process in the U.S., especially after the disaster of the emergency approval of the COVID shots that we know now not only failed to prevent infection, were actually very harmful to many.

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August 16, 2023 Quick space links

3:14 pm

Courtesy of BtB’s stringer Jay.

 

 

 

 

 

 

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West Virginia University: to save money it eliminates 32 majors instead of its bloated overhead

1:15 pm

West Virginia University logo
West Virginia University: An example of bankrupt academia?

Bankrupt academia: The bankruptcy of intellectual thought in modern American academia is finally beginning to percolate down to the bankbook, at least in West Virginia. On August 11, 2023 the administration at West Virginia University released a report proposing the elimination of 32 majors while also eliminating 169 faculty positions.

The preliminary recommendations, released Friday afternoon, said 12 of those programs are undergraduate majors and 20 are graduate-level majors. Other programs were told to reduce their faculty size — 169 faculty jobs are on the line for cuts.

Programs marked for discontinuation included: master’s and doctorate in Mathematics; master’s and doctorate in Higher Education Administration; master’s of Public Administration; master’s of fine arts in Creative Writing; and a bachelor’s in Recreation, Parks and Tourism Resources. The Department of World Languages, Literatures and Linguistics, which includes Spanish, Russian and Chinese studies, was marked to be completely dissolved.

You can read the full report here. It is important to look closely at it, as it reveals some stark facts about how bankrupt academia remains. » Read more

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An avalanche in the West Virginia of Mars

11:53 am

An avalanche in the West Virginia of Mars
Click for original image.

Cool image time! The picture to the right, rotated, cropped, and reduced to post here, was taken on June 27, 2023 by the high resolution camera on Mars Reconnaissance Orbiter (MRO).

I have cropped it to focus on this one hill, about 900 feet high (though the elevation data from MRO is somewhat uncertain at this resolution), because of that major landslide on its northern slopes. At some point in the past a major piece of the exposed bedrock at the top broke off and slide about halfway down the mountain, almost as a unit, settling on the alluvial fill that comprises the bottom half of the hill’s flanks.

The bedrock surrounding the peak is also of interest because of its gullies, all of which were created by downward flowing material. Was it ice? Water? Sand? Or maybe a combination of two or three? If water or ice was involved it was a very long time ago, as this location is in the dry equatorial regions of Mars. There is little known near-surface ice here.
» Read more

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Scientists discover in Alaska the largest dinosaur track site in U.S.

9:51 am

New dinosaur track site in Alaska
Click for original image.

Paleontologists have discovered in Alaska a new dinosaur track site that appears to contain numerous exposed tracks on what is now a series of vertical walls covering an area larger than a football field.

The picture to the right shows the entire site. The darker flat walls that appear to be dimpled are the track sites, with the dimples the actual tracks.

Researchers at the University of Alaska Fairbanks made the discovery following a seven-hour hike into the Denali National Park and Preserve, and it is now the home of the largest known single dinosaur track site in the US state.

Like a geological triple-decker (or more) sandwich, the 20-story-high structure, pushed vertical due to tectonic plate convergence, reveals a cliff face of layer upon layer of preserved prints throughout time. “It’s not just one level of rock with tracks on it,” said Dustin Stewart, the paper’s lead author and a former UAF graduate student. “It is a sequence through time. Up until now, Denali had other track sites that are known, but nothing of this magnitude.”

The scientists think these now vertical walls, when horizontal in the past, marked a major water-hole location visited by numerous dinosaurs and other species.

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SpaceX report on first Starship/Superheavy launch failure submitted to FAA

9:34 am

Though we don’t know exactly when this was done, SpaceX has submitted to the FAA its final report on its investigation into the launch failure during the first Starship/Superheavy test launch in April, and now awaits the FAA’s response.

Now comes the FAA’s review of SpaceX’s investigation, fulfilling the agency’s role as the regulator charged with ensuring public safety during commercial launch operations. “When a final mishap report is approved, it will identify the corrective actions SpaceX must make,” an FAA spokesperson told Ars. “Separately, SpaceX must modify its license to incorporate those actions before receiving authorization to launch again.

Do not expect that response to be fast, or accepting. I predict the FAA will demand a lot more investigation and changes from SpaceX, actions that will take time to implement and be approved. Furthermore, I fully expect the FAA to take at least two months to review the SpaceX report before it issues those demands. As I have been predicting since May, there will be no Superheavy/Starship launch this year.

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Astra scrambling to find investors as its cash reserves dwindle

9:27 am

Despite a major reorganization, including laying off a quarter of its workforce, Astra now appears to be scrambling to find new investors even as its available cash reserves shrink.

The company’s financial runway is diminishing even as the company finds new sources of capital, such as a loan announced Aug. 4 that will provide Astra with $10.8 million and plans announced in July to sell up to $65 million in Astra stock in an “at-the-market” transaction. The company forecasted an adjusted EBITDA loss of $25 million to $29 million in the third quarter, ending the quarter with $15 million to $20 million of cash and equivalents on hand.

One analyst on the call expressed frustration with those projections, asking Astra executives for the “upside” of the company’s plans. Kemp emphasized the backlog of orders for its thrusters, which Astra said Aug. 4 was valued at $77 million, as well as orders from the U.S. Space Force and the Defense Innovation Unit for the Rocket 4.

However, he suggested the company’s efforts to focus on thruster production were intended to buy time for Astra as the company looks for new investors. The company said Aug. 4 it was working with PJT Partners, an investment bank, to identify “potential strategic investments in the Astra Spacecraft Engine business” that would bolster its finances. “We are actively focused on finding investors in these two businesses,” he said, noting that the company’s launch and spacecraft propulsion business lines are distinct and “in different phases of their development.”

Essentially the company is approaching a make-or-break moment. What I think is likely to happen is it will either go bankrupt, or be purchased outright by a new big-money investor who will take over the company entirely, replacing its present management with new people.

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Russia considering flying Proton rockets after 2025

9:19 am

According to a story today in Russia’s state-run TASS news outlet, the Khrunichev design bureau that builds Russia’s Proton rocket is in negotiation with Kazahkstan to use all the remaining Proton rockets available, even if that requires additional launches after 2025, the date Roscosmos had previously announced as when all Proton launches will cease.

The Khrunichev Center (part of the state-run space corporation Roscosmos) is actively working on future cooperation with the Kazakh side, including with regard to the use of the Proton carrier rocket, the center’s CEO Alexey Varochko told TASS. “The Khrunichev Center is actively working on various scenarios of mutually beneficial cooperation with the Kazakh side, including those involving the Proton carrier rocket,” Varochko said.

According to the official, the possibility of using Protons after 2025 may be considered only if both Russia and Kazakhstan give their consent.

It sounds like Khrunichev has some spare Protons, and wants to make some money from them, even if Roscosmos has forbid it. It also appears that there is political infighting within Roscosmos about the retirement of Proton and resulting the loss of government jobs at Khrunichev.

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Chandrayaan-3 reaches final lunar orbit for landing

9:12 am


Click for interactive map.

India’s Chandrayaan-3 spacecraft completed its final lunar orbital engine burn today, placing it in the correct orbit to release the lander Vikram, carrying the Pragyan rover.

The release is scheduled for tomorrow, with the landing targeting August 23, 2023. This will be India’s second attempt to softland an unmanned probe on the Moon. The Vikram lander of Chandrayaan-2 failed in 2019 during its final engine burn above the surface, crashing thereafter. Engineers at India’s space agency ISRO spent several years upgrading that lander to better insure this new attempt would succeed.

The lander has been given more ability to manoeuvre during the descent, the mission allows for a bigger 4 km x 2.4 km area for landing, more sensors have been added, one of the thrusters has been removed, and the legs of the lander have been made sturdier to allow for landing even at slightly higher velocity. More solar panels have also been added to ensure that the mission can go on even if the lander does not face the sun. More tests to see the capability of the lander in different situations were carried out to make Chandrayaan-3 more resilient.

Both Vikram and Russia’s Luna-25 lander, scheduled for touchdown on August 21, will land in the high southern latitudes of the Moon, at about 70 degrees. They are not going to the Moon’s south pole, as many news reports claim.

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August 15, 2023 Quick space links

3:23 pm

Courtesy of BtB’s stringer Jay.

 

 

  • NASA is developing a larger cubesat adapter for SLS

    • It will allow SLS to carry more cubesats that are bigger. Whether any commercial cubesat company will want to fly on it remains unknown, considering the uncertainty of any SLS launch. Jay also notes many comments on X about “cubesats dying while waiting for [an SLS] launch.”

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We are becoming a nation of barbarians

2:16 pm

From Netflix's Barbarians series
Making heroes of barbarians, on Netflix

I have previous railed against the decline in the use of language in the United States. Not only do Americans now routinely use obscenities in normal language, they have been meekly acquiescing to the demands of the radical and somewhat insane queer movement to accept its weasel words in order to hide what it really is.

The recent viral and passionate endorsement by conservatives of all stripes to a new song and the performance by a new country singer, Oliver Anthony, illustrates how this decline to barbarism is accelerating. The focus of Anthony’s song is the cruel destruction of the American way of life by the power-brokers in Washington, and how those power brokers are making life so difficult for ordinary people.

What makes Anthony’s song indicative however of society’s increasing barbarous trend is his language. Right from the start he nonchalantly uses obscenities that would have once been considered unacceptable by everyone, and until recently utterly unacceptable among our more conservative population.

Yet now, even conservatives see nothing wrong with Anthony’s use of obscenities. Apparently, it is now okay for everyone to spew curse words everywhere, in public, in songs, for all to hear, from children to adults. Anthony’s message condemning the tyranny coming from Washington is too important to ignore. It must be touted widely, no matter how obscenely he couches his statement.

In other words, now even conservatives don’t care if our culture is debased and damaged. It doesn’t matter if we teach young children that they can act like barbarians, cursing and expressing wild emotions without thinking. It is policy and political power that matters, not doing right and behaving properly.

For though curses and obscenities have their place and proper time, in a civilization of rational civil adults one does not encourage their use. » Read more

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The impact that almost cracked Mars open

12:40 pm

An irregular pit chain on Mars
Click for original image.

Cool image time! The picture to the right, rotated, cropped, reduced, and sharpened to post here, was taken on June 25, 2023 by the high resolution camera on Mars Reconnaissance Orbiter (MRO). It shows what the scientists label an “irregular pit chain,” made up of a series of depressions scattered along a line that extends more than sixty miles to the northeast and to the southwest, beyond the edges of this high resolution close-up.

The chain likely indicates the existence of a fault line, or crack that created a void underground in which surface material is sinking. What makes this crack or fault line significant is how it and other similar fissures or cracks map across the Martian surface, extending for thousands of miles far beyond this particular pit chain and covering almost half the planet. In aggregate they imply the occurrence of past geological events so stupendous they are difficult to comprehend.
» Read more

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Ingenuity’s 55th flight completed

9:57 am

Overview map
Click for interactive map.

The Ingenuity engineering team today updated the helicopter’s flight log, showing that the 55th flight occurred on August 12, 2023, one day later than originally planned, and flew 881 feet for 143 seconds, 61 feet and 9 seconds longer than planned.

The overview map above shows the present locations of both Perseverance and Ingenuity. The green dot marks Ingenuity’s new position, while the blue dot marks where Perseverance presently sits in Jezero Crater. Based on this map, the main goal of the flight was apparently to fly Ingenuity over a route that Perseverance will likely use to return to its planned route, as indicated by the red dotted line.

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Webb confirms galaxy as one of the earliest known in the universe

9:27 am

The uncertainty of science: Using the spectroscopic instrument on the Webb Space Telescope, scientists have confirmed that one of the first galaxies found by Webb, dubbed Maisie’s Galaxy after the daughter of one scientist, is one of the earliest known in the universe, existing only 390 million years after when cosmologies say the Big Bang happened.

The data also showed that another one of these early galaxies spotted by Webb did not exist 250 million years after the Big Bang, but one billion years after, a date that better fits the theories about the early universe, based on the nature of this galaxy.

It turns out that hot gas in CEERS-93316 was emitting so much light in a few narrow frequency bands associated with oxygen and hydrogen that it made the galaxy appear much bluer than it really was. That blue cast mimicked the signature Finkelstein and others expected to see in very early galaxies. This is due to a quirk of the photometric method that happens only for objects with redshifts of about 4.9. Finkelstein says this was a case of bad luck. “This was a kind of weird case,” Finkelstein said. “Of the many tens of high redshift candidates that have been observed spectroscopically, this is the only instance of the true redshift being much less than our initial guess.”

Not only does this galaxy appear unnaturally blue, it also is much brighter than our current models predict for galaxies that formed so early in the universe. “It would have been really challenging to explain how the universe could create such a massive galaxy so soon,” Finkelstein said. “So, I think this was probably always the most likely outcome, because it was so extreme, so bright, at such an apparent high redshift.”

This science team is presently using Webb’s spectroscope to study ten early galaxies in order to better determine their age. Expect more results momentarily.

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Intuitive Machines sets mid-November launch date for its Nova-C lunar lander

9:16 am


Click for interactive map.

Intuitive Machines announced yesterday that the launch of its lunar lander, Nova-C, is now targeting a November 15-20, 2023 window, lifting off on a SpaceX Falcon 9 rocket.

The yellow dot on the map to the right indicates the landing site, Malapert A, in the southern latitudes of the Moon. The white cross indicates the south pole.

The lander had originally planned to launch in 2021, but delays in construction pushed the launch back two years. A second company, Astrobotics, has its own lander, Peregrine, that though also delayed two years, has been ready to launch since early this year. It won’t launch until the end of this year at the earliest, however, due to delays in readying its rocket, ULA’s Vulcan on its first flight.

Both India’s Chandrayaan-3 and Russia’s Luna-3 are right now on their way to the Moon, with each planning a landing next week.

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Busby Berkeley – Tap dance sequence from Lullaby of Broadway

6:01 pm

An evening pause: Time for another Berkeley extravaganza. This except is only a small part of the full thirteen-plus minute Lullaby of Broadway number in the movie Gold Diggers of 1935. This movie was made when the talking pictures were still new, and making films that highlighted “All Talking! All Singing! All Dancing!” was the rage. It was also a time when all Americans danced arm-in-arm as one of their main forms of entertainment, so interest in great dancing like this was at its height.

Hat top Judd Clark.

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August 14, 2023 Quick space links

4:47 pm

Courtesy of BtB’s stringer Jay.

 

 

 

 

 

 

 

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Today’s blacklisted American: Gestapo police in Kansas raid home of 98-year-old newspaper owner, causing her death

12:44 pm

Joan Meyer
Joan Meyer, now dead because of police raid

On August 11, 2023 the entire police department of Marion, Kansas, performed a Gestapo-like raid of the home of 98-year-old Joan Meyer, co-owner of the local newspaper, the Marion County Record, resulting in her death from a heart attack the next day.

The elderly woman, who co-owned the newspaper with her son Eric, was subjected to the raid by five officers and two sheriff’s deputies on Friday – which caused her to be ‘stressed beyond her limits and overwhelmed by hours of shock and grief.’ Eric, 69, has bashed the officers for their ‘Gestapo’ tactics in an attempt to seize information that hadn’t even gone to presses yet. Police have defended their actions.

Ms Meyer could not eat or sleep after the traumatizing hours-long ordeal. She was crying while the police raided her home and took her Alexa smart speaker – and died one day later. [emphasis mine]

It appears the police also that day raided the newspaper’s offices as well as the home of one of its reporters.

And why? All the evidence suggests this is a case of a local businesswoman working in teamwork with the police and a local judge to harass and destroy a newspaper. From the second link:
» Read more

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Residual ice on the shaded north-facing slope of northern Martian crater

11:32 am

Residual ice on Mars?
Click for original image.

Cool image time! The picture to the right, rotated, cropped, reduced, and sharpened to post here, was taken on April 10, 2023 by the high resolution camera on Mars Reconnaissance Orbiter (MRO). In the headline I am speculating a bit when I call that pile of material bunched up against the interior slope of this unnamed 18-mile-wide crater residual ice. No data is available to me that proves that assumption, but the look, the location, and the general previous data from Mars all tell me that this is what it is.

First, the location within the crater. Everyone who has lived in the northern latitudes where snow falls knows that snow will remain in the shaded slopes that face north — where less direct sunlight falls — much longer than in places where there is more sunlight. You can sometimes even find this residual snow as late as June and July in some such spots.

This phenomenon will be no different on Mars. In those alcoves this material, which looks exactly like glacial features found in many other places in the mid-latitudes of Mars (such as inside the small half-mile-wide crater in the lower left), is well protected, so that even when the rest of the ice sublimated away within the crater it remained. The cliff wall rises five hundred feet to the south, blocking sunlight so that for most of the year little directly sunlight touches this surface.
» Read more

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China makes available to the international community Chang’e-5’s lunar samples

9:52 am

China on August 2, 2023 announced that it is now allowing scientists from all nations to apply for access to the lunar samples brought back to Earth by its 2020 Chang’e-5 mission to the Moon.

The announcement outlined very specific rules for the loan of the samples, including requirements that if any part of a sample needs to be destroyed to study it that action be videotaped in detail. Samples loaned for research are for one year periods only, though this can be extended.

The rules also allow two month loans for the use of samples in public display, such as at a museum.

In both cases China will closely supervise the research and retain the right to recall the samples at any time if it doesn’t approve of what the borrower is doing.

U.S. law forbids our government officials or agencies from working with China, so don’t expect NASA or its scientists to apply for these samples. However, the law doesn’t apply to independent scientists, though serious state department regulations would apply. I therefore doubt many American scientists will apply for any samples. It would carry too many risks to their other research.

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Scientist creates longest time-lapse movie of exoplanet circling its star

9:37 am

A scientist at Northwestern University has used seventeen years of data to create the longest time-lapse movie yet of an exoplanet circling its star, Beta Pictoris, which is located 63 light years away.

Constructed from real data, the footage shows Beta Pictoris b — a planet 12 times the mass of Jupiter — sailing around its star in a tilted orbit. The time-lapse video condenses 17 years of footage (collected between 2003 and 2020) into 10 seconds. Within those seconds, viewers can watch the planet make about 75% of one full orbit.

“We need another six years of data before we can see one whole orbit,” said Northwestern astrophysicist Jason Wang, who led the work. “We’re almost there. Patience is key.”

I have embedded the video below. Because the star in the center is so bright, its light is blocked out, so that this part of the planet’s orbit is represented by the “X” in the video.
» Read more

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Chandrayaan-3 completes next-to-last orbital maneuver before releasing Vikram lander

9:31 am


Click for interactive map.

According to India’s ISRO space agency, its Chandrayaan-3 spacecraft has successfully completed the next-to-last orbital maneuver burn before releasing Vikram lander, lowering the spacecraft’s orbit around the Moon to 150 by 177 kilometers.

Today’s maneuver can be considered the second last vital maneuver. The one that takes place on August 16, will set the course for the Vikram lander.

Based on how today’s and August 16’s manoeuvres are executed, ISRO will get to decide where the Vikram lander touches down, among three predesignated spots on the Moon’s surface.

It had been my understanding that the landing zone was as indicated by the red dot on the map to the right. It might be instead that was only one of three potential landing sites. If so, I will update the map when more data is released.

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Axiom signs deal with Poland and ESA to send Polish astronaut to Axiom’s future space station

9:22 am

Capitalism in space: Axiom last week signed an agreement jointly with Poland and the European Space Agency (ESA) to send Polish astronaut to Axiom’s space station, expected to launch sometime in 2026.

This was the second European astronaut Axiom has signed a deal to fly to space, with the ESA in both cases providing support.

In April 2023, Axiom Space and the Swedish National Space Agency signed a letter of intent to send an ESA astronaut to the ISS. Through this agreement, the upcoming Axiom Space mission, Ax-3 now targeting launch in January 2024, will be the first commercial mission to the ISS to include an ESA project astronaut.

The date for the flight of the Polish astronaut was not announced. Nor is it clear whether this astronaut will fly to Axiom’s first module, attached to ISS, or wait until Axiom’s completes its station and separates from ISS entirely.

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China’s solid-fueled Kuaizhou-1A rocket launches five smallsats

9:14 am

China yesterday launched five smallsats using its solid fueled Kuaizhou-1A rocket, lifting off from its Xichang spaceport in the south of China.

It was the second launch from Xichang yesterday. Unlike the Long March 3B, which uses very toxic hypergolic fuels, the Kuaizhou-1A uses solid fuels in its lower three stages (the fourth in orbit is liquid-fueled), which are not as toxic but still somewhat unhealthy. As with the earlier launch, however, those lower stages crashed somewhere in China. No word whether they landed near habitable areas.

The leaders in the 2023 launch race:

55 SpaceX
35 China
11 Russia
6 Rocket Lab
6 India

American private enterprise still leads China in successful launches 63 to 35, and the entire world combined 63 to 57. SpaceX by itself now trails the entire world (excluding American companies) 55 to 57.

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China’s Long March 3B launches radar satellite

9:03 am

China's spaceports
China’s spaceports

China early today used its Long March 3B two-stage rocket (plus four strap-on boosters) to put a radar satellite into geosynchronous orbit, lifting off from its Xichang spaceport in southern interior China.

The orbit required the rocket to travel almost due east, which means the first stage and all four boosters crashed over China’s eastern heavily populated provinces, as shown on the map to the right. All use toxic hypergolic fuels. No word if the stages landed on any cities, as China’s communist government does without any qualms.

The leaders in the 2023 launch race:

55 SpaceX
34 China
11 Russia
6 Rocket Lab
6 India

American private enterprise still leads China in successful launches 63 to 34, and the entire world combined 63 to 56. SpaceX by itself now trails the entire world (excluding American companies) 55 to 56.

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August 11, 2023 Quick space links

3:20 pm

Courtesy of BtB’s stringer Jay.

 

 

 

 

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The flat and mostly featureless flood lava plains of Mars

2:39 pm

The flat and mostly featureless lava plains of Mars
Click for original image.

Cool image time! The picture to the right, rotated, cropped, reduced, and sharpened to post here, was taken on July 3, 2023 by the high resolution camera on Mars Reconnaissance Orbiter (MRO). Dubbed a “terrain sample” by the camera team, it was likely taken not as part of any scientist’s specific research program but to fill a gap in the camera’s schedule in order to maintain its proper temperature. When the camera team needs to do this they try to pick something of interest that is below during that gap.

In this case MRO was over the vast flood lava plains of Mars where for many hundreds of miles the only features are small variations produced from different overlapping lava flood events. The layers of lava in this region in fact appear so thick that there are relatively few places where the older topography still sticks up through the lava. In the case of this picture, the ridges might indicate such buried topography, but they also might simply be dikes of lava, pushed up through fissures from underground.
» Read more

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