Author: Robert Zimmerman

ISS research suggests weightlessness accelerates aging in stem cells

8:58 am

According to a study that flew stem cells on four separate missions to ISS ranging in length from 32 to 45 days, weightlessness appears to age stem cells significantly.

Researchers from University of California San Diego Sanford Stem Cell Institute have discovered that spaceflight accelerates the aging of human hematopoietic stem and progenitor cells (HSPCs), which are vital for blood and immune system health. In a study published in Cell Stem Cell, the team used automated artificial intelligence (AI)-driven stem cell-tracking nanobioreactor systems in four SpaceX Commercial Resupply Services missions to the International Space Station (ISS) to track stem cell changes in real time. The findings show that the cells lost some of their ability to make healthy new cells, became more prone to DNA damage and showed signs of faster aging at the ends of their chromosomes after spaceflight — all signs of accelerated aging.

Upon return to Earth the study also found the cells recovered somewhat.

You can read the peer-reviewed paper here.

In a sense, this study confirms what numerous other research has found, that weightlessness mimics the conditions of old age, and causes the same physical decline seen in the elderly. It also shows that much of that damage in weightlessness is transient, recovering upon return to Earth.

This research once again highlights the imperative need to study the impact on various levels of artificial gravity on the human body. Will producing a 10% g environment — using centrifugal force — mitigate these negative impacts? Or will we have to simulate a full 1 g environment? Or something in between?

The first option is much easier in terms of engineering. The last will be complex and take time to develop.

At the moment almost no research has been done in this area. And it needs to happen soon, if people intend to go to Mars in the near future. Such journeys, six months minimum in weightlessness, are likely to leave the passengers somewhat debilitated upon arrival, no matter how much they exercise along the way. And being debilitated is not a good condition for a pioneer trying to build a new civilization on an alien world.

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NASA and Northrop Grumman work out rendezvous plan to get Cygnus to ISS

11:08 pm

UPDATE: The plan worked and Cygnus is safely berthed at ISS.

According to a press release tonight, NASA and Northrop Grumman have figured out a new rendezvous plan to get Cygnus to ISS after its previous engine burns yesterday cut off prematurely and left it in the wrong orbit.

NASA and Northrop Grumman are targeting the safe arrival of the company’s Cygnus XL at approximately 7:18 a.m. EDT Thursday, Sept. 18, to the International Space Station. The Cygnus XL now will conduct a series of burns to bring the spacecraft to the space station for its robotic capture and installation.

NASA astronaut Jonny Kim is scheduled to capture Cygnus XL using the station’s Canadarm2 robotic arm with backup support from NASA astronaut Zena Cardman. After capture, the spacecraft will be installed on the Unity module’s Earth-facing port and will remain at the space station until March 2026.

The release also added this detail about why that engine burn ended too soon:

Data shared by the spacecraft confirmed that Cygnus XL operated as intended during two planned maneuvers when an early warning system initiated a shutdown command and ended the main engine burn because of a conservative safeguard in the software settings.

Apparently this cause has reassured them that the engine is in good shape for the final rendezvous burns.

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September 17, 2025 Quick space links

3:01 pm

Courtesy of BtB’s stringer Jay. This post is also an open thread. I welcome my readers to post any comments or additional links relating to any space issues, even if unrelated to the links below.

  • ESA delivers to NASA the third service module for Orion
    The first was used on the Artemis-1, that went around the Moon unmanned in 2022. The second will be used on the first manned mission, presently scheduled for April 2026 to also fly around the Moon. This third service module will be used on the planned landing mission, Artemis-3, scheduled for 2027 (very unlikely).
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Monitoring the largest recent impact detected by InSight’s seismometer

11:51 am

Overview

Cool image time! On December 24, 2021 the seismometer of the Mars lander InSight detected a four magnitude earthquake, the largest detected up until then. Because its nature suggested that it had been caused by an impact, not an internal shifting, the science team for Mars Reconnaissance Orbiter (MRO) immediately started searching for new impact craters in the area of Mars where the data suggested the quake came from.

Two months later they found it, in the northern lowland plains just south of the prime landing zone chosen by SpaceX for its Starship spacecraft. The black cross on the overview map to the right indicates the position. The four red spots are the prime Starship landing sites. The white dots indicate other locations considered. The black dots were images taken for a proposed Dragon landing. This impact is thus only about 100 miles away from the nearest possible Starship landing spot.
» Read more

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Premature engine cutoff forces postponement of Cygnus berthing to ISS

11:16 pm

During the second of two engine burns today, designed to raise the orbit of Northrop Grumman’s Cygnus freighter to match ISS’s, the burn ended prematurely, placing the capsule in the wrong orbit.

Early Tuesday morning, Cygnus XL’s main engine stopped earlier than planned during two burns designed to raise the orbit of the spacecraft for rendezvous with the space station, where it will deliver 11,000 pounds of scientific investigations and cargo to the orbiting laboratory for NASA. All other Cygnus XL systems are performing normally.

The berthing, using one of the robot arms on ISS, had been planned for early tomorrow, Wednesday, but will not occur until both NASA and Northrop Grumman engineers have analyzed the issues and come up with “an alternate burn plan”.

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September 16, 2025 Quick space links

3:10 pm

Courtesy of BtB’s stringer Jay. This post is also an open thread. I welcome my readers to post any comments or additional links relating to any space issues, even if unrelated to the links below.

6 comments

Strange unexplained polarization shifts in M87’s supermassive black hole

12:25 pm

The changing magnetic field of M87
Click for original image.

Using the Event Horizon Telescope (EHT), astronomers have detected unexpected and so far unexplained polarization shifts in the supermassive black hole that resides at the center of the galaxy M87, located 55 million light years away.

That black hole is estimated to have a mass six billion times that of our Sun, and was the first ever imaged by EHT. By using observations made in 2017, 2018, and 2021, as shown in the images to the right, found its magnetic field changing in unexpected ways.

Between 2017 and 2021, the polarization pattern flipped direction. In 2017, the magnetic fields appeared to spiral one way; by 2018, they settled; and in 2021, they reversed, spiraling the opposite direction. Some of these apparent changes in the polarization’s rotational direction may be influenced by a combination of internal magnetic structure and external effects, such as a Faraday screen. The cumulative effects of how this polarization changes over time suggests an evolving, turbulent environment where magnetic fields play a vital role in governing how matter falls into the black hole and how energy is launched outward.

The changes were more puzzling in that the size of the black hole’s event horizon, the ring surrounding it, did not change. According to the scientists, this suggests “magnetized plasma swirling near the event horizon is far from static; it’s dynamic and complex, pushing our theoretical models to the limit.”

That the magnetic field flipped polarity however should not be surprising to scientists. Consider the same polarity flips we see in our own Sun every eleven years. It should be expected that the magnetic field around a super massive black hole would be equally variable, if not more so.

The problem is that there remains no understanding about why such changes happen. We know the magnetic field exists. We know it flips polarity. With the Sun we know it does so regularly every eleven years. Why it does so however remains unknown, though there are theories. With M87 the data is far less certain.

Tracking the changes at M87 however should help us build our knowledge base so that someday we might finally grasp those fundamentals.

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Isar outlines what caused the failure on the first launch of its Spectrum rocket

11:13 am

Isar's first launch attempt fails
Spectrum falling seconds after launch

According to officials of the German rocket startup Isar Aerospace, its Spectrum rocket failed during its first launch in March 2025 because of a loss of attitude control, which then caused the rocket to self-destruct.

Alexandre Dalloneau, vice president of mission and launch operations at Isar, said that the company had not properly characterized bending modes of the vehicle at liftoff. “The controllability has to be tuned in order to counter such behavior,” he said. That environment was not fully modeled and incorporated into the vehicle’s control system. “We were outside the environment that we expected, so that the controllability does not succeed.”

That loss of attitude control caused the vehicle to go outside the safety zone at the launch site. That, in turn, triggered the flight termination system on the rocket. He said the company has revised its modeling of vehicle modes at liftoff to correct the problem.

The company is now working towards a second launch from Norway’s Andoya spaceport, which it hopes to attempt either late this year or early next year. Afterward it hopes to launch eight-plus times a year, based on the demand it is presently seeing for its rocket.

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Europe once again delays test flights of its Callisto 1st stage hopper

11:05 am

Callisto's basic design
Callisto’s basic design

First proposed in 2015 as Europe’s answer to SpaceX’s Falcon 9, the first test flights of the European Space Agency (ESA)’s Callisto grasshopper-type reusable test prototype, as shown on the right, has once again been delayed, now from 2026 to 2027.

On Friday, CNES published a call seeking a partner to provide mechanical operations and procedures support ahead of the Callisto flight-test campaign, including contributions to operations user manuals, drafting mechanical operation procedures, and conducting detailed studies of mechanical interfaces between the vehicle and the ground segment. In the preamble to the scope of work, the notice states that the campaign will be carried out from the Guiana Space Centre in French Guiana in 2027. It will include an integration phase followed by eight test flights and two demonstration flights, all to be completed over a period of eight months.

The project, in which Japan’s space agency JAXA is participating, had an initial budget of $100 million, and originally planned to do its first hops in 2020. Instead, ESA spent a dozen years making powerpoint presentations, while SpaceX flew hundreds of operational flights with its Falcon 9, for profit.

Worse, this program is not attached to any rocket. It is a dead end. ESA and JAXA might get some useful engineering data from it, but it will belong to no one, and it is unclear anyone will care. At this moment it appears several private companies in Europe will have flown their own new rockets before Callisto even gets off the ground, and the data from those real rocket launches will be much more useful to them down the road.

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