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The estimated lose to the U.S. economy due to the shutdown over the Wuhan panic is now estimated at $32 trillion, more than the entire annual gross national product for the country.
That number is of course preliminary, but for a first guess I think it is probably low, especially because it does not include the following:
It also assumes we get back to work relatively soon. Should the shut down extend through May, I think the Great Depression will appear like a lark in comparison.
Note that the overall social cost of this panic and shutdown cannot be measured, as it is also establishing new social distancing customs that are probably overwrought and counter-productive for a healthy society.