Astronaut blood samples suggest long-term exposure to weightlessness causes brain damage
New research comparing blood samples taken from five Russian astronauts before and after long term missions to ISS suggests that weightlessness can cause brain damage.
Published in JAMA Neurology, the new research looked at five male Russian cosmonauts. Each spent an average of 169 days in space. Blood samples were taken from each subject before leaving Earth, and then at three points after returning.
Five different blood-based biomarkers were measured, each known to correlate with some kind of brain damage. Three biomarkers in particular were found to be significantly elevated after the cosmonauts returned to Earth – neurofilament light (NfL), glial fibrillary acidic protein (GFAP), and a specific type of amyloid beta protein.
The researchers hypothesize the increases in NfL and GFAP levels may indicate a type of neurodegeneration called axonal disintegration. Elevated NfL levels are currently being investigated as a way of detecting the earliest stages of brain damage associated with Alzheimer’s disease.
It must be emphasized that the research did not find brain damage, only data within the blood samples that is often associated with brain damage. More research is required to determine if these biomarkers indicate the same thing in space as they do on Earth.
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Your help allows me to do this kind of intelligent analysis. I take no advertising or sponsors, so my reporting isn't influenced by donations by established space or drug companies. Instead, I rely entirely on donations and subscriptions from my readers, which gives me the freedom to write what I think, unencumbered by outside influences.
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New research comparing blood samples taken from five Russian astronauts before and after long term missions to ISS suggests that weightlessness can cause brain damage.
Published in JAMA Neurology, the new research looked at five male Russian cosmonauts. Each spent an average of 169 days in space. Blood samples were taken from each subject before leaving Earth, and then at three points after returning.
Five different blood-based biomarkers were measured, each known to correlate with some kind of brain damage. Three biomarkers in particular were found to be significantly elevated after the cosmonauts returned to Earth – neurofilament light (NfL), glial fibrillary acidic protein (GFAP), and a specific type of amyloid beta protein.
The researchers hypothesize the increases in NfL and GFAP levels may indicate a type of neurodegeneration called axonal disintegration. Elevated NfL levels are currently being investigated as a way of detecting the earliest stages of brain damage associated with Alzheimer’s disease.
It must be emphasized that the research did not find brain damage, only data within the blood samples that is often associated with brain damage. More research is required to determine if these biomarkers indicate the same thing in space as they do on Earth.
Readers!
Please consider supporting my work here at Behind the Black. Your support allows me the freedom and ability to analyze objectively the ongoing renaissance in space, as well as the cultural changes -- for good or ill -- that are happening across America. Fourteen years ago I wrote that SLS and Orion were a bad ideas, a waste of money, would be years behind schedule, and better replaced by commercial private enterprise. Only now does it appear that Washington might finally recognize this reality.
In 2020 when the world panicked over COVID I wrote that the panic was unnecessary, that the virus was apparently simply a variation of the flu, that masks were not simply pointless but if worn incorrectly were a health threat, that the lockdowns were a disaster and did nothing to stop the spread of COVID. Only in the past year have some of our so-called experts in the health field have begun to recognize these facts.
Your help allows me to do this kind of intelligent analysis. I take no advertising or sponsors, so my reporting isn't influenced by donations by established space or drug companies. Instead, I rely entirely on donations and subscriptions from my readers, which gives me the freedom to write what I think, unencumbered by outside influences.
You can support me either by giving a one-time contribution or a regular subscription. There are four ways of doing so:
1. Zelle: This is the only internet method that charges no fees. All you have to do is use the Zelle link at your internet bank and give my name and email address (zimmerman at nasw dot org). What you donate is what I get.
2. Patreon: Go to my website there and pick one of five monthly subscription amounts, or by making a one-time donation.
3. A Paypal Donation or subscription:
4. Donate by check, payable to Robert Zimmerman and mailed to
Behind The Black
c/o Robert Zimmerman
P.O.Box 1262
Cortaro, AZ 85652
You can also support me by buying one of my books, as noted in the boxes interspersed throughout the webpage or shown in the menu above.
For one thing, the sample size is ridiculously small. How many people have actually spent time in space?
If this turns out to be confirmed by further studies, we are going to need some form of artificial gravity for our trips to Mars.
So what you’re saying is the United States suffered a loss in gravity the past two years?
Great place for animal studies. Treatments for brain diseases have potential economic value exceeding space exploration budgets
Explains Senator Kelly
Here Be Dragons!
Pink Floyd / Mars Direct
“Set The Controls For The Heart Of The Sun”
https://youtu.be/a9ntxCcjVjE
9:47
It explains Pakleds ;/ On a serious note…I see weightlessness as a form of dialysis…a way to shed disease markers before they can hide?
John: So what you’re saying is the United States suffered a loss in gravity the past two years?
Not the entire nation … just DC, a few state capitals, and several of our largest urban areas.