Chinese scientists do genetic experiments with human embryos

What could possibly go wrong? A Chinese team of scientists have been experimenting with genetically manipulating the human embryo to see if they can prevent a genetic blood disorder.

The team attempted to modify the gene responsible for β-thalassaemia, a potentially fatal blood disorder, using a gene-editing technique known as CRISPR/Cas9. The researchers say that their results reveal serious obstacles to using the method in medical applications. “I believe this is the first report of CRISPR/Cas9 applied to human pre-implantation embryos and as such the study is a landmark, as well as a cautionary tale,” says George Daley, a stem-cell biologist at Harvard Medical School in Boston. “Their study should be a stern warning to any practitioner who thinks the technology is ready for testing to eradicate disease genes.”

They not only found the technique unreliable in curing the genetic disease, it also produced many more unpredicted mutations.

Genesis cover

On Christmas Eve 1968 three Americans became the first humans to visit another world. What they did to celebrate was unexpected and profound, and will be remembered throughout all human history. Genesis: the Story of Apollo 8, Robert Zimmerman's classic history of humanity's first journey to another world, tells that story, and it is now available as both an ebook and an audiobook, both with a foreword by Valerie Anders and a new introduction by Robert Zimmerman.

 

The print edition can be purchased at Amazon, any other book seller, or direct from my ebook publisher, ebookit. The ebook is available everywhere for $5.99 (before discount) at amazon, or direct from my ebook publisher, ebookit you don't support the big tech companies and the author gets a bigger cut much sooner.


The audiobook is also available at all these vendors, and is also free with a 30-day trial membership to Audible.
 

"Not simply about one mission, [Genesis] is also the history of America's quest for the moon... Zimmerman has done a masterful job of tying disparate events together into a solid account of one of America's greatest human triumphs."--San Antonio Express-News

The first reflected light from an exoplanet detected

For the first time scientists have detected directly the reflected light coming from an exoplanet.

Astronomers using the HARPS planet-hunting machine at ESO’s La Silla Observatory in Chile have made the first-ever direct detection of the spectrum of visible light reflected off an exoplanet. These observations also revealed new properties of this famous object, the first exoplanet ever discovered around a normal star: 51 Pegasi b. The result promises an exciting future for this technique, particularly with the advent of next generation instruments, such as ESPRESSO, on the VLT, and future telescopes, such as the E-ELT.

Conscious Choice cover

Now available in hardback and paperback as well as ebook!

 

From the press release: In this ground-breaking new history of early America, historian Robert Zimmerman not only exposes the lie behind The New York Times 1619 Project that falsely claims slavery is central to the history of the United States, he also provides profound lessons about the nature of human societies, lessons important for Americans today as well as for all future settlers on Mars and elsewhere in space.

 
Conscious Choice: The origins of slavery in America and why it matters today and for our future in outer space, is a riveting page-turning story that documents how slavery slowly became pervasive in the southern British colonies of North America, colonies founded by a people and culture that not only did not allow slavery but in every way were hostile to the practice.  
Conscious Choice does more however. In telling the tragic history of the Virginia colony and the rise of slavery there, Zimmerman lays out the proper path for creating healthy societies in places like the Moon and Mars.

 

“Zimmerman’s ground-breaking history provides every future generation the basic framework for establishing new societies on other worlds. We would be wise to heed what he says.” —Robert Zubrin, founder of the Mars Society.

 

All editions are available at Amazon, Barnes & Noble, and all book vendors, with the ebook priced at $5.99 before discount. All editions can also be purchased direct from the ebook publisher, ebookit, in which case you don't support the big tech companies and the author gets a bigger cut much sooner.

 

Autographed printed copies are also available at discount directly from the author (hardback $29.95; paperback $14.95; Shipping cost for either: $6.00). Just send an email to zimmerman @ nasw dot org.

Russia slashes spending on space

In the heat of competition: Economic hard times have forced the Russian government to cut spending on its space program by more than a third.

The cuts have mainly come from abandoning their effort to build a heavy lift rocket to compete with SLS. They might not realize it, but I think this will be a blessing in disguise, as they will no longer be wasting money building a giant rocket that will have little value in the competitive launch market. Instead, they will focus their investment on Angara, which has the possibility of earning them a profit.

Meanwhile, however, they still have to deal with the quality control problems and corruption that appears to permeate Russia`s entire aerospace industry: Russian defense rocket fails and crashes immediately after launch. I have posted the video of the crash below the fold. It appears that the rocket was successfuly propelled from its launch silo, but then its rocket engines never ignited.
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The building rage is not just against Democrats

People who read my website only intermittently might get the impression that I am partisan and specifically hostile to the Democratic Party. This is false. I am an equal opportunity opponent to anyone that likes oppression and the use of government to impose it.

Some stories today, describing the actions or opinions of some of the so-called conservative or moderate leaders of both the Republican and Democratic parties, illustrate clearly that we still need a major house-cleaning in Congress if we are to get this out-of-control monster under control:
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Leaving Earth cover

Leaving Earth: Space Stations, Rival Superpowers, and the Quest for Interplanetary Travel, can be purchased as an ebook everywhere for only $3.99 (before discount) at amazon, Barnes & Noble, all ebook vendors, or direct from my ebook publisher, ebookit.

 

If you buy it from ebookit you don't support the big oppressive tech companies and I get a bigger cut much sooner.

 

Winner of the 2003 Eugene M. Emme Award of the American Astronautical Society.

 
"Leaving Earth is one of the best and certainly the most comprehensive summary of our drive into space that I have ever read. It will be invaluable to future scholars because it will tell them how the next chapter of human history opened." -- Arthur C. Clarke

Hubble finds something astronomers can’t explain

The uncertainty of science: The Hubble Space Telescope has spotted the explosion of a star that does not fit into any theory for stellar evolution.

The exploding star, which was seen in the constellation Eridanus, faded over two weeks — much too rapidly to qualify as a supernova. The outburst was also about ten times fainter than most supernovae, explosions that destroy some or all of a star. But it was about 100 times brighter than an ordinary nova, which is a type of surface explosion that leaves a star intact. “The combination of properties is puzzling,” says Mario Livio, an astrophysicist at the Space Telescope Science Institute in Baltimore, Maryland. “I thought about a number of possibilities, but each of them fails” to account for all characteristics of the outburst, he adds.

We can put this discovery on the bottom of a very long list of similar discoveries by Hubble, which this week is celebrating the 25th anniversary of its launch.

On that note, as part of that celebration Space.com today has published a long interview with me about Hubble and my book, The Universe in a Mirror, the saga of the Hubble Space Telescope and the visionaries who built it. They have also published an excerpt from the book. Check both out.

New Shepard test flights to begin within weeks

The competition heats up: Blue Origin is expected to begin regular test flights of its suborbital resusable manned spacecraft, New Shepard, within mere weeks.

This news came from a government FAA official involved in approving flight permits. The company itself has declined to comment.

Even if it is a few months rather than weeks, these flight tests will put more pressure on Virgin Galactic in the race to become the first commercial suborbital tourism company to sell and actually fly a passenger. And if I had to bet who’d win the race, I would no longer put my money on Virgin Galactic.

NASA ISS cargo contracts delayed

The competition heats up: NASA has delayed, for the second time, when it will award its next round of cargo contracts to ISS, pushing the date back from June to September.

Though agency officials said they could not reveal why they had delayed the contract awards, they did say it was to gather more information. My guess is that the agency wants to see how SpaceX’s launch abort tests turn out this year before it makes a decision. If successful, they will then have the option of dropping SpaceX’s as a cargo carrier and pick someone else, possibly Dream Chaser, to provide up and down service to ISS. That way, they would increase the number of vehicles capable of bringing people and supplies up to ISS.

Delaying the award decision until September gives them time to evaluate the abort tests results, as well as give them a cushion in case those tests get delayed somewhat.

Liberals may regret their new rules

Link here. Two quotes:

Which brings us to America in 2015. It’s becoming a nation where an elite that is certain of its power and its moral rightness is waging a cultural war on a despised minority. Except it’s not actually a minority – it only seems that way because it is marginalized by the coastal elitist liberals who run the mainstream media.

Today in America, we have a liberal president refuses to recognize the majority sent to Congress as a reaction to his progressive failures, and who uses extra-Constitutional means like executive orders to stifle the voice of his opponents. We have a liberal establishment on a secular jihad against people who dare place their conscience ahead of progressive dogma. And we have two different sets of laws, one for the little people and one for liberals like Lois Lerner, Al Sharpton and Hillary Clinton, who can blatantly commit federal crimes and walk away scot free and smirking.

Today in America, a despised minority that is really no minority is the target of an establishment that considers this minority unworthy of respect, unworthy of rights, and unworthy of having a say in the direction of this country. It’s an establishment that has one law for itself, and another for its enemies. It’s an establishment that inflicts an ever-increasing series of petty humiliations on its opponents and considers this all hilarious.

That’s a recipe for disaster. You cannot expect to change the status quo for yourself and then expect those you victimize not to play by the new rules you have created. You cannot expect to be able to discard the rule of law in favor of the rule of force and have those you target not respond in kind.

And this:

When you block all normal means of dissent, whether by ignoring the political will of your opponents or using the media to mock and abuse them, you build up the pressure. In 30+ years as an active conservative, I’ve never heard people so angry, so frustrated, so fed up. These emotions are supposed to be dissipated by normal political processes. But liberals are bottling them up. And they will blow. It’s only a matter of how.

Liberals need to understand the reality that rarely penetrates their bubble. Non-liberal Americans (it’s more than just conservatives who are under the liberal establishment’s heel) are the majority of this country. They hold power in many states and regions in unprecedented majorities. And these attacks focus on what they hold dearest – their religion, their families and their freedom.

What is the end game, liberals? Do you expect these people you despise to just take it? Do you think they’ll just shrug their shoulders and say, “Well, I guess we better comply?” Do you even know any real Americans? Do you think you’ll somehow be able to force them into obedience – for what is government power but force – after someone finally says “Enough?

Read it all. I can’t quote it all, but every word carries a wisdom that the left — as well as the status quo Republican establishment — better heed before it is too late.

As I’ve said before, the rage is building.

I am also reminded of this scene, below the fold, from the 1966 masterpiece A Man for All Seasons:
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Protesters prevent minorities from attending class

Fascists: In order to protest what they preceive as a hostile environment on campus for minorities, protesters blocked access to the school so that minorities could not attend classes.

Up to 50 students gathered and prevented foot traffic through the gate. On multiple occasions, students, including minorities, tried to break through so they could attend class. In response, the protesters violently attacked them. Three assaults were reported during the protest. The University of California Police Department (UCPD) at Berkeley did not take action against the protesters, despite the fact that they acknowledged that protesters were breaking the rules and potentially committed crimes.

You can’t make this stuff up. To highlight oppression these fascists impose oppression. According to the article, the protest only ended when students teamed up and “bull-rushed” the protesters in order to get to their classes.

Rosetta records the appearance of a new jet on Comet 67P/C-G

jet appears on comet

Cool image time! Images taken two minutes apart by Rosetta have captured the emergence of a new jet on Comet 67P/C-G.

The two images released today show the remarkable onset of such a jet for the first time. They were taken on 12 March from a distance of 75 kilometres. In the first image, obtained at 07:13 CET, several rays of dust jets frame the upper, illuminated side of the comet. The dark underside shows no such features. Two minutes later, the picture has changed: a spectacular new jet has emerged on the dark side, hurtling dust into space and displaying a clearly discernable fine structure.

This was the first jet observed in a shadowed area, and the scientists think this jet might have started because it was just before dawn there.

More strikes at Vostochny

Another worker strike has broken out at the new Russian spaceport at Vostochny by workers who say they have not been paid their wages.

The strike itself is not the significant fact here. The significant fact is that even though the project has been under the close supervision of Putin himself since September, the wages were still not paid. Supervisors have been pocketing wages even as very high Russian officials have been publicly demanding that they get the construction back on schedule. And this story suggests that they continue to do so.

The entire situation implies a very extensive level of corruption at all levels of the Russian infrastructure, something that will make it very difficult for them to accomplish much in their future efforts in space.

Japan to the moon!

The competition heats up: Japan’s space agency has announced plans to send an unmanned lander to the Moon, as early as 2018, as part of a longer range plan to explore Mars.

They also intend to use their new Epsilon rocket to launch it.

Gee, I wonder if the successful efforts of India and China to send probes to both the Moon and Mars had some influence on this decision.

TMT construction postponed again

The builders of the Thirty Meter Telescope have temporarily extended the suspension of construction originally demanded by Hawaii’s governor.

The tone of the article, especially the comments by the governor, suggests that the state is accepting the reality that they have no legal right to stop construction, and are making that fact very public. Instead, the govenor is now beginning the public relations campaign to make construction possible despite the protests, including negotiating some other givebacks to the protesters to shut them up. Sadly, those giveback appear to be the decommissioning of some other working telescopes as well as some increased restrictions on access to the mountain by the public.

Incorrectly built SLS welding machine to be rebuilt

You can’t make this stuff up. A giant welding machine, built for NASA’s multi-billion dollar Space Launch System (SLS), needs to be rebuilt because the contractor failed to reinforce the floor, as required, prior to construction.

Sweden’s ESAB Welding & Cutting, which has its North American headquarters in Florence, South Carolina, built the the roughly 50-meter tall Vertical Assembly Center as a subcontractor to SLS contractor Boeing at NASA’s Michoud Assembly Facility in New Orleans.

ESAB was supposed to reinforce Michoud’s floor before installing the welding tool, but did not, NASA SLS Program Manager Todd May told SpaceNews after an April 15 panel session during the 31st Space Symposium here. As a result, the enormous machine leaned ever so slightly, cocking the rails that guide massive rings used to lift parts of the 8.4-meter-diameter SLS stages The rings wound up 0.06 degrees out of alignment, which may not sound like much, “but when you’re talking about something that’s 217 feet [66.14 meters] tall, that adds up,” May said.

Asked why ESAB did not reinforce the foundation as it was supposed to, May said only it was a result of “a miscommunication between two [Boeing] subcontractors and ESAB.”

How everyone at NASA, Boeing, and ESAB could have forgotten to do the reinforcing, even though it was specified in the contract, baffles me. It also suggests that the quality control in the SLS rocket program has some serious problems.

Update: The original story at Space News that I originally linked to disappeared sometime in the next week, and was replaced with a slightly more detailed and more positive story, now linked above.

Sierra Nevada and Germany sign agreement

The competition heats up: Sierra Nevada has signed a new development agreement with Germany in connection with its Dream Chaser reusable mini-shuttle.

The agreement does not appear to involve any money and thus is largely symbolic. Nonetheless, it shows again that Germany is interested in having Dream Chaser built, and is throwing its support behind the manned spacecraft.

Russia delays first manned launch from Vostochny

The Russian government has decided to delay from 2018 to 2020 the first manned launch from its new spaceport at Vostochny because an earlier launch would require them to use equipment they expect to retire anyway.

While the construction problems at Vostochny might be a factory in this decision, I also believe there is truth to the claim above. If they launch in 2018, they will probably have to use the Soyuz rocket to launch crews into space. By 2020 they plan to have Angara completely operational, and will be ready to retire Soyuz. Why build the infrastructure for Soyuz when you plan to retire it in only a couple of years anyway?

The delay however indicates a more fundamental problem with the Russian top-down authoritarian culture. It shouldn’t take them this long to get Angara operational. The rocket was conceived shortly after the fall of the Soviet Union in the early 1990s. They’ve had almost a quarter century to build it. Even though they’ve only just done the first two test flights, there is no justification for it to take another five years to get all the configurations of the rocket flying.

If they want to compete on the world market, they are going to have to work faster than this. A competitive private company, rather than delaying the launch, would have pushed Angara to be ready sooner so that the the launch could happen on time, with Angara. That the Russians seem unable to do this indicates that they will not be very competitive in the coming decades.

SpaceX is considering a ground landing for its next first stage return attempt

The competition heats up: After its second attempt this week to land its first stage on a barge in the Atlantic, SpaceX is now considering landing their next attempt on the ground.

This shouldn’t be a surprise. The reason they have been landing over the ocean in these initial tests was for safety. The last two landings however had demonstrated that they can reliably bring that first stage back accurately and precisely. Since they have the ability to destroy the stage should it go off course, it seems reasonable to shift to land now and simplify their challenge.

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