Half the facts you know are wrong.The uncertainty of science: Half the facts you know are wrong.
Facts are being manufactured all of the time, and, as Arbesman shows, many of them turn out to be wrong. Checking each one is how the scientific process is supposed to work; experimental results need to be replicated by other researchers. So how many of the findings in 845,175 articles published in 2009 and recorded in PubMed, the free online medical database, were actually replicated? Not all that many. In 2011, a disquieting study in Nature reported that a team of researchers over 10 years was able to reproduce the results of only six out of 53 landmark papers in preclinical cancer research.
In 2005, the physician and statistician John Ioannides published “Why Most Published Research Findings Are False” in the journal PLoS Medicine. Ioannides cataloged the flaws of much biomedical research, pointing out that reported studies are less likely to be true when they are small, the postulated effect is likely to be weak, research designs and endpoints are flexible, financial and nonfinancial conflicts of interest are common, and competition in the field is fierce. Ioannides concluded that “for many current scientific fields, claimed research findings may often be simply accurate measures of the prevailing bias.”
Or in other words, anyone who claims the “science is settled” on any major scientific issue that other scientists are hotly debating is lying to you.
On Christmas Eve 1968 three Americans became the first humans to visit another world. What they did to celebrate was unexpected and profound, and will be remembered throughout all human history. Genesis: the Story of Apollo 8, Robert Zimmerman's classic history of humanity's first journey to another world, tells that story, and it is now available as both an ebook and an audiobook, both with a foreword by Valerie Anders and a new introduction by Robert Zimmerman.
The print edition can be purchased at Amazon or from any other book seller. If you want an autographed copy the price is $60 for the hardback and $45 for the paperback, plus $8 shipping for each. Go here for purchasing details. The ebook is available everywhere for $5.99 (before discount) at amazon, or direct from my ebook publisher, ebookit. If you buy it from ebookit you don't support the big tech companies and the author gets a bigger cut much sooner.
The audiobook is also available at all these vendors, and is also free with a 30-day trial membership to Audible.
"Not simply about one mission, [Genesis] is also the history of America's quest for the moon... Zimmerman has done a masterful job of tying disparate events together into a solid account of one of America's greatest human triumphs."--San Antonio Express-News
The uncertainty of science: Half the facts you know are wrong.
Facts are being manufactured all of the time, and, as Arbesman shows, many of them turn out to be wrong. Checking each one is how the scientific process is supposed to work; experimental results need to be replicated by other researchers. So how many of the findings in 845,175 articles published in 2009 and recorded in PubMed, the free online medical database, were actually replicated? Not all that many. In 2011, a disquieting study in Nature reported that a team of researchers over 10 years was able to reproduce the results of only six out of 53 landmark papers in preclinical cancer research.
In 2005, the physician and statistician John Ioannides published “Why Most Published Research Findings Are False” in the journal PLoS Medicine. Ioannides cataloged the flaws of much biomedical research, pointing out that reported studies are less likely to be true when they are small, the postulated effect is likely to be weak, research designs and endpoints are flexible, financial and nonfinancial conflicts of interest are common, and competition in the field is fierce. Ioannides concluded that “for many current scientific fields, claimed research findings may often be simply accurate measures of the prevailing bias.”
Or in other words, anyone who claims the “science is settled” on any major scientific issue that other scientists are hotly debating is lying to you.
On Christmas Eve 1968 three Americans became the first humans to visit another world. What they did to celebrate was unexpected and profound, and will be remembered throughout all human history. Genesis: the Story of Apollo 8, Robert Zimmerman's classic history of humanity's first journey to another world, tells that story, and it is now available as both an ebook and an audiobook, both with a foreword by Valerie Anders and a new introduction by Robert Zimmerman.
The print edition can be purchased at Amazon or from any other book seller. If you want an autographed copy the price is $60 for the hardback and $45 for the paperback, plus $8 shipping for each. Go here for purchasing details. The ebook is available everywhere for $5.99 (before discount) at amazon, or direct from my ebook publisher, ebookit. If you buy it from ebookit you don't support the big tech companies and the author gets a bigger cut much sooner.
The audiobook is also available at all these vendors, and is also free with a 30-day trial membership to Audible.
"Not simply about one mission, [Genesis] is also the history of America's quest for the moon... Zimmerman has done a masterful job of tying disparate events together into a solid account of one of America's greatest human triumphs."--San Antonio Express-News
A lot of research isn’t replicated because finding similar results won’t get you published. When it comes to drug studies, these can be very expensive to reproduce. Nevertheless, this article is scary.