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As I do every July, it is once again time for my annual anniversary fund-raising campaign to support this website and the work I do here.

 

This year I celebrate Behind the Black’s sixteenth anniversary. In those sixteen years I have done more than 35,000 posts (which means I added more than 2,000 in the last year), with my main focus covering the global space industry and the related planetary and astronomical science that comes from it. Along the way I sometimes also post my thoughts on the politics and culture of the time, partly because I think it is important for free Americans to do so, and partly because those politics and culture have a direct impact on the future of our civilization and its on-going efforts to explore and eventually colonized the solar system.

 

You can’t understand one without understanding the other.

 

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Pharmaceutical company to use Varda’s capsules to manufacture heart drugs in space

Varda's W-5 capsule after landing today
Varda’s fifth capsule after landing on January 29, 2026

The pharmaceutical company United Therapeutics Corporation has purchased space on an unspecified number of future Varda’s recoverable capsules so that it can manufacture pulmonary drugs in space.

Through the collaboration, Varda and United Therapeutics will conduct pharmaceutical processing of small molecule medicines for pulmonary disease aboard Varda’s orbital manufacturing and reentry platform during multiple missions to low Earth orbit.

The companies will utilize microgravity’s influence on the structure and crystallization properties of therapeutic compounds in pursuit of novel formulations that may improve stability, bioavailability, and other delivery characteristics. The first compounds to be analyzed onboard Varda spacecraft will likely be focused on therapies for patients living with life-threatening pulmonary diseases.

Varda has a deal in Australia to land 20 more capsules through 2028. This deal helps fill the payload space on those capsules.

As I have noted repeatedly, there is money to be made manufacturing drugs in weightlessness for later sale back on Earth, a reality that NASA has blocked on ISS for decades. Varda is now grabbing that market, which is also why a lot of investment capital has become available for a whole slew of proposed competing recoverable capsule companies.

Genesis cover

On Christmas Eve 1968 three Americans became the first humans to visit another world. What they did to celebrate was unexpected and profound, and will be remembered throughout all human history. Genesis: the Story of Apollo 8, Robert Zimmerman's classic history of humanity's first journey to another world, tells that story, and it is now available as both an ebook and an audiobook, both with a foreword by Valerie Anders and a new introduction by Robert Zimmerman.

The print edition can be purchased at Amazon or from any other book seller. If you want an autographed copy the price is $60 for the hardback and $45 for the paperback, plus $8 shipping for each. Go here for purchasing details. The ebook is available everywhere for $5.99 (before discount) at amazon, or direct from my ebook publisher, ebookit. If you buy it from ebookit you don't support the big tech companies and the author gets a bigger cut much sooner.


The audiobook is also available at all these vendors, and is also free with a 30-day trial membership to Audible.
 

"Not simply about one mission, [Genesis] is also the history of America's quest for the moon... Zimmerman has done a masterful job of tying disparate events together into a solid account of one of America's greatest human triumphs."--San Antonio Express-News

3 comments

3 comments

  • wayne

    “Varda Space Industries has not publicly named a specific heart drug as its current manufacturing target in space, but its work is focused on crystallizing pharmaceuticals.”

    “The company’s most recent high-profile success was crystallizing the HIV drug Ritonavir in orbit, which demonstrated the potential of microgravity to produce drug crystals with superior uniformity and novel polymorphs.”

    –>The key word here is “polymorphs.”

    “In crystallography, polymorphism is the phenomenon where a compound or element can crystallize into more than one crystal structure. These different solid forms are called polymorphs, and they share the same chemical composition but differ in the arrangement of atoms, molecules, or ions in the crystal lattice. Polymorphs are not chemically different substances; they are the same molecule or element in different solid arrangements, and result in different pharmaceutical effects.”

    “Crystal Polymorphism”
    Veritasium (April, 2026)
    https://youtu.be/ksn5yrsC3Wg
    33:24

  • Cotour

    An interesting tour of VARDA’s facility: https://youtu.be/fhAOD2Sdo2c?si=IaikDSV4fYkP6xaH

    Not a publicly traded company.

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